Pretty much Immortal ~Kinda in-depth Guide~
by MythicalPlatypus
Faustian Bargain
Rune of Travel no longer automatically activates, and if the Rune is not used the Cooldown is reset.
Rune of Travel
Revitalize
Rune of Travel heals you for 100-500 when you teleport to it.
Rune of Travel
4
Primeval Might
Gain 8-40% lifesteal while Overcharge is active.
Overcharge
3
Evanescent
Move 8-40% faster while Rune of Travel is active.
Rune of Travel
1
Perseverance
Gain 10-50% lifesteal when below 40% health.
Weapon
2
Guts
Take 6-30% less damage when below 40% health.
Armor
5
Guide
Faustian Bargain so you don't waste your 400 heal on RoT and always have an amazing escape.
Revitalize ^
Primeval Might is just crazy good and can save you and win a lot of 1v1's.
Evanescent not too important but that 8% movespeed can be really good since you almost always have your RoT active.
Perseverance, when combined with GUTS and Primeval Might, is what makes you truly makes you immortal with this loadout.
as far as items it is really up to you, But here's some tips.
Blue: Haven / Blast Shield > Resilience.
Resilience can help you avoid CC. but I prefer reducing damage, If they have any good AoE source then I go Blast shield since you can zip around pretty quick to avoid direct damage. Otherwise, Haven is a nice boon.
Yellow: Nimble > Chronos > Morale Boost.
Nimble if you need extra move speed to dodge direct attacks because you had to pick up Blast Shield to avoid AoE.
Chronos if you don't need Nimble. It can really help your Rune of Travel come back up in time for the next engagement after having to use it.
Green: Kill to Heal.
You are a flanker in the Enemies backline 9 times out of 10 (Away from your healer) so Kill to Heal is your best of friends. You don't really need more lifesteal than you already have, Rejuvenate would mean you need to be closer to your healer and Veteran isn't really going to help you in a fight plus your Rune of Travel heals you well enough.
Red: Cauterize > Wrecker > Deft Hands.
Cauterize if they have great healing abilities.
Wrecker if they have someone like Ruckus with big boy shields.
Deft hands if you want to have infinite ammo :P.